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Indicated for: Epilepsy (Lennox-Gastaut Syndrome, Akinetic Seizures, Myoclonic Seizures, Absence Seizures, Focal Seizures, Infantile Spasms), Panic Disorder with or without Agoraphobia, Generalized Anxiety Disorder (Short-term Adjunctive Therapy), Restless Legs Syndrome (Refractory), Rapid Eye Movement Sleep Behavior Disorder, Acute Mania (Adjunctive), Neuroleptic-Induced Akathisia, Acute Alcohol Withdrawal Syndrome, Sleep Bruxism, Trigeminal Neuralgia (Off-label Adjunctive), Stiff Person Syndrome.
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Taking it too late could leave the patient unprotected during the first cycles of REM sleep. The maximum recommended daily dose of Klonopin for the management of severe, treatment-refractory Panic Disorder is 4 mg, and even this level is reached only after a prolonged period of gradual, incremental, and carefully monitored titration in a very small and highly selected subset of patients. This is not a starting dose, nor is it a regimen that is contemplated for the mild to moderate, situational, or transient anxieties that are a common and expected part of the human experience.
Medicine To Help You Stay Awake. For the patient in Vancouver or Adelaide, this means that while Klonopin may not be altering the long-term prognosis associated with the brainstem synucleinopathy, it is providing an absolutely crucial and humane intervention in the here and now: it is keeping them and their loved ones safe during the vulnerable hours of sleep, preserving quality of life and functional independence for as long as possible while the broader field of neurology races to develop disease-modifying therapies.
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